Objectives: The aim of this article is to describe the culture as a dynamic system over which various factors have influence; political / dynamics of the political situation in the Balkans and in particular in Ruse /, environmental factors / the extreme influence of the Danube on the city /. Prior Work: Exploration of cultural variability according to the views of Kluckhohn and Strodbeck, Edward Hall and Geert Hofstede and to what extent the ethnic groups living on the territory of the city of Ruse in the reviewed period illustrate them. Approach: Theoretical clarification of cultural variability and practical research of how it is addressed in two contexts material and spiritual. Results: The general conclusion drawn in the paper is that the local community in  Ruse combines the contemporary concepts of multiculturalism and the variance of values and their application traced in a diachronic aspect. Implications: The article can initiate a discussion concerning notions as multiculturalism, cultural variability on the territory of the Danube region. Value: The local community of Ruse and its contacts with other cultural communities and established attitudes of tolerance and, at the same time, the sustainability and continuity of values can be given as a good example in a time of growing multiculturalism and globalization, both in Europe and world wide.