The possibility of implementing a student-centred approach to the organization of independent work is justified by grouping students according to similar parameters of the individual characteristics of each person dominant in learning according to the criterion of "learning opportunities" into typological dynamic multi-level groups, which allows organizing independent work at different levels of requirements and different methods. The criteria characteristics of each dynamic typological group of students are considered and in accordance with this, a system of multi-level tasks (creative, search and reproductive) is created, which contributes to students' independent choice of tasks of different levels of complexity, methods of cognitive activity. It is proved that independent work organized on the principle of a student-centred approach, provides for its organization, according to which students studying in one program, have the right and opportunity to assimilate it at different planned levels, but not lower than the level of mandatory results, which creates conditions for the transition of everyone from one group to another, higher level. The prospects of further scientific research are determined by the study of psychological and pedagogical determinants of improving the organization of independent work of students.