Danubius International Conferences, 16th International Conference on European Integration - Realities and Perspectives

Comparative Study of Two Sensors Performances Regarding the Detection of L-Phenylalanine and L-Tyrosine

Ancuta Dinu (Iacob), Constantin Apetrei
Last modified: 2021-05-12

Abstract

Phenylalanine and Tyrosine are two important amino acids for the human body; there is an interdependent relationship between them. Phenylalanine is transformed into tyrosine and metabolized in the liver, but both amino acids are precursors for the neurotransmitters dopamine, adrenaline, and noradrenaline. Persons with high concentrations of phenylalanine in the body fluids may develop an inherited metabolic disease called phenylketonuria (PKU), and their bodies are unable to produce tyrosine. Following these considerations, the present paper describes the electroanalytical performances of two sensors observed by cyclic voltammetry for the detection of these two amino acids. The developed sensors demonstrated high performance characteristics, and can be successfully applied in the detection of the two amino acids in both human serum and drug supplements.

 

Acknowledgments: This work is supported by the project “ANTREPRENORDOC”, in the framework of Human Resources Development Operational Programme 2014-2020, financed from the European Social Fund under the contract number 36355/23.05.2019 HRD OP /380/6/13 – SMIS Code: 123847.